A straightforward asymmetric synthesis of 1,2-disubstituted ferrocenylalkyl amines with the unusual (S(Fc),S) configuration.

نویسندگان

  • Guillaume Grach
  • Jean-François Lohier
  • Jana Sopkova-de Oliveira Santos
  • Vincent Reboul
  • Patrick Metzner
چکیده

A useful synthesis of rare 1,2-disubstituted ferrocenylalkyl amines with (S(Fc),S) configuration has been achieved in a sequential one-pot methodology from (S)-p-tolylsulfinylferrocene.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

An Efficient One Pot Procedure for Preparation of Symmetrical N,N'-Disubstituted Urea from Aromatic and Aliphatic Amines and Urea under Microwave Irradiation

A phosgene-free synthesis of symmetrical N,N'-disubstituted urea by the reaction of aromatic and aliphatic primary amines and urea promoted by  microwave irradiation in the presence of a suitable energy-transfer solvent such as N-N-dimethylacetamide is described.

متن کامل

Synthesis of 1,2-Disubstituted Benzimidazoles in the Presence of SBA-Pr-SO3H as a Nano Solid Acid Catalyst

In this article, simple, convenient synthesis of 2-aryl-1- arylmethyl-1H-1,3-benzimidazole (1,2-disubstituted benzimidazoles) via condensation of 1,2-phenylenediamine and aromatic aldehydes using SBA-Pr-SO3H as a nanoporous solid acid catalyst in green protocol was reported.

متن کامل

A Bioinspired Catalytic Aerobic Oxidative C–H Functionalization of Primary Aliphatic Amines: Synthesis of 1,2-Disubstituted Benzimidazoles

Aerobic oxidative CH functionalization of primary aliphatic amines has been accomplished with a biomimetic cooperative catalytic system to furnish 1,2-disubstituted benzimidazoles that play an important role as drug discovery targets. This one-pot atom-economical multistep process, which proceeds under mild conditions, with ambient air and equimolar amounts of each coupling partner, constitute...

متن کامل

Preparation of Some Meso-Disubstituted Anthracenes

The synthesis of some 9,10-disubstituted anthracene derivatives are described. 9,10-Bis(2-bromoethyl) anthracene 4,9,10-Bis (2-cyanoethyl) anthracene 5 and 9,10-Bis (4-hydroxybutyl) anthracene 11 are synthesized for the first time.

متن کامل

One-pot synthesis of diverse N,N'-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines via N-phthaloyl-guanidines.

A sequential one-pot approach towards N,N'-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol also features wide substrate scope and mild conditions.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 46  شماره 

صفحات  -

تاریخ انتشار 2007